| Rank | Title | Year | Director(s) |
| 1240 | Sabrina | 1954 | Billy Wilder |
| 1202 | The Sacrifice | 1986 | Andrei Tarkovsky |
| 1547 | Safe | 1995 | Todd Haynes |
| 687 | Safety Last! | 1923 | Fred C. Newmeyer and Sam Taylor |
| 2642 | Saint Maud | 2019 | Rose Glass |
| 1683 | Salaam Bombay! | 1988 | Mira Nair |
| 1250 | Salesman | 1969 | Albert and David Maysles and Charlotte Zwerin |
| 1247 | Salň | 1975 | Pier Paolo Pasolini |
| 2009 | Salvador | 1986 | Oliver Stone |
| 2361 | Salvatore Giuliano | 1962 | Francesco Rosi |
| 455 | Le Samouraď | 1967 | Jean-Pierre Melville |
| 1764 | Samurai Rebellion | 1967 | Masaki Kobayashi |
| 3018 | San Francisco | 1936 | W.S. Van Dyke |
| 2795 | The Sand Pebbles | 1966 | Robert Wise |
| 913 | The Sandlot | 1993 | David Mickey Evans |
| 2055 | Sands of Iwo Jima | 1949 | Allan Dwan |
| 1900 | Sanjuro | 1962 | Akira Kurosawa |
| 700 | Sans soleil | 1983 | Chris Marker |
| 414 | Sansho the Bailiff | 1954 | Kenji Mizoguchi |
| 2469 | Santa Sangre | 1989 | Alejandro Jodorowsky |
| 2459 | The Saragossa Manuscript | 1965 | Wojciech Has |
| 776 | Sátántangó | 1994 | Béla Tarr |
| 1190 | Saturday Night and Sunday Morning | 1960 | Karel Reisz |
| 780 | Saturday Night Fever | 1977 | John Badham |
| 2977 | Saving Face | 2004 | Alice Wu |
| 60 | Saving Private Ryan | 1998 | Steven Spielberg |
| 828 | Saw | 2004 | James Wan |
| 615 | Say Anything… | 1989 | Cameron Crowe |
| 1449 | A Scanner Darkly | 2006 | Richard Linklater |
| 2024 | Scanners | 1981 | David Cronenberg |
| 220 | Scarface | 1983 | Brian De Palma |
| 665 | Scarface | 1932 | Howard Hawks |
| 1434 | The Scarlet Empress | 1934 | Josef von Sternberg |
| 2398 | Scarlet Street | 1945 | Fritz Lang |
| 1018 | Scenes from a Marriage | 1974 | Ingmar Bergman |
| 1572 | Scent of a Woman | 1992 | Martin Brest |
| 21 | Schindler's List | 1993 | Steven Spielberg |
| 977 | The School of Rock | 2003 | Richard Linklater |
| 1331 | Scorpio Rising | 1963 | Kenneth Anger |
| 691 | Scott Pilgrim vs. the World | 2010 | Edgar Wright |
| 310 | Scream | 1996 | Wes Craven |
| 2739 | Scream 2 | 1997 | Wes Craven |
| 2178 | Scrooge | 1951 | Brian Desmond Hurst |
| 2752 | Scum | 1979 | Alan Clarke |
| 1488 | The Sea Inside | 2004 | Alejandro Amenábar |
| 1639 | Seabiscuit | 2003 | Gary Ross |
| 53 | The Searchers | 1956 | John Ford |
| 2731 | Searching for Bobby Fischer | 1993 | Steven Zaillian |
| 1646 | Searching for Sugar Man | 2012 | Malik Bendjelloul |
| 2836 | Second Breath | 1966 | Jean-Pierre Melville |
| 901 | Seconds | 1966 | John Frankenheimer |
| 1938 | The Secret Garden | 1993 | Agnieszka Holland |
| 1391 | The Secret in Their Eyes | 2009 | Juan José Campanella |
| 1769 | The Secret of Kells | 2009 | Tomm Moore |
| 1156 | The Secret of NIMH | 1982 | Don Bluth |
| 2556 | The Secret World of Arrietty | 2010 | Hiromasa Yonebayashi |
| 1981 | Secretary | 2002 | Steven Shainberg |
| 629 | Secrets & Lies | 1996 | Mike Leigh |
| 796 | Selma | 2014 | Ava DuVernay |
| 949 | Senna | 2010 | Asif Kapadia |
| 668 | Sense and Sensibility | 1995 | Ang Lee |
| 1700 | Senso | 1954 | Luchino Visconti |
| 548 | A Separation | 2011 | Asghar Farhadi |
| 2641 | Serendipity | 2001 | Peter Chelsom |
| 755 | Serenity | 2005 | Joss Whedon |
| 1056 | Sergeant York | 1941 | Howard Hawks |
| 2603 | Serial Mom | 1994 | John Waters |
| 1203 | A Serious Man | 2009 | Ethan and Joel Coen |
| 825 | Serpico | 1973 | Sidney Lumet |
| 1000 | The Servant | 1963 | Joseph Losey |
| 2823 | Session 9 | 2001 | Brad Anderson |
| 2203 | Set It Off | 1996 | F. Gary Gray |
| 1801 | The Set-Up | 1949 | Robert Wise |
| 90 | Seven | 1995 | David Fincher |
| 1805 | Seven Beauties | 1975 | Lina Wertmüller |
| 1392 | Seven Brides for Seven Brothers | 1954 | Stanley Donen |
| 2712 | Seven Chances | 1925 | Buster Keaton |
| 2776 | Seven Days in May | 1964 | John Frankenheimer |
| 1462 | Seven Men from Now | 1956 | Budd Boetticher |
| 1394 | Seven Plus Seven | 1970 | Michael Apted |
| 2812 | Seven Pounds | 2008 | Gabriele Muccino |
| 24 | Seven Samurai | 1954 | Akira Kurosawa |
| 1227 | Seven Up! | 1964 | Paul Almond |
| 1317 | The Seven Year Itch | 1955 | Billy Wilder |
| 2654 | Seventh Heaven | 1927 | Frank Borzage |
| 118 | The Seventh Seal | 1957 | Ingmar Bergman |
| 2314 | The Seventh Victim | 1943 | Mark Robson |
| 909 | Sex, Lies, and Videotape | 1989 | Steven Soderbergh |
| 1147 | Sexy Beast | 2000 | Jonathan Glazer |
| 425 | Shadow of a Doubt | 1943 | Alfred Hitchcock |
| 669 | Shadows | 1958 | John Cassavetes |
| 1762 | Shadows of Forgotten Ancestors | 1965 | Sergei Parajanov |
| 866 | Shaft | 1971 | Gordon Parks |
| 1026 | Shakespeare in Love | 1998 | John Madden |
| 2500 | Shallow Grave | 1994 | Danny Boyle |
| 1979 | Shame | 2011 | Steve McQueen |
| 2480 | Shame | 1968 | Ingmar Bergman |
| 2676 | Shampoo | 1975 | Hal Ashby |
| 410 | Shane | 1953 | George Stevens |
| 2834 | Shang-Chi and the Legend of the Ten Rings | 2021 | Destin Daniel Cretton |
| 1827 | Shanghai Express | 1932 | Josef von Sternberg |
| 3041 | Shaolin Master Killer | 1978 | Chia-Liang Liu |
| 1945 | Shaolin Soccer | 2001 | Stephen Chow |
| 1100 | The Shape of Water | 2017 | Guillermo del Toro |
| 214 | Shaun of the Dead | 2004 | Edgar Wright |
| 2198 | Shaun the Sheep Movie | 2015 | Mark Burton and Richard Starzak |
| 45 | The Shawshank Redemption | 1994 | Frank Darabont |
| 2548 | Shazam! | 2019 | David F. Sandberg |
| 2766 | She Done Him Wrong | 1933 | Lowell Sherman |
| 1013 | She Wore a Yellow Ribbon | 1949 | John Ford |
| 3012 | Sherlock Holmes | 2009 | Guy Ritchie |
| 281 | Sherlock, Jr. | 1924 | Buster Keaton |
| 1644 | Sherman's March | 1985 | Ross McElwee |
| 1087 | She's Gotta Have It | 1986 | Spike Lee |
| 2607 | Shine | 1996 | Scott Hicks |
| 22 | The Shining | 1980 | Stanley Kubrick |
| 2815 | Shiva Baby | 2020 | Emma Seligman |
| 2773 | Shivers | 1975 | David Cronenberg |
| 254 | Shoah | 1985 | Claude Lanzmann |
| 1624 | Shock Corridor | 1963 | Samuel Fuller |
| 2120 | Shoeshine | 1946 | Vittorio De Sica |
| 2007 | Sholay | 1975 | Ramesh Sippy |
| 1291 | Shoot the Piano Player | 1960 | François Truffaut |
| 1887 | The Shooting | 1966 | Monte Hellman |
| 1226 | The Shootist | 1976 | Don Siegel |
| 260 | The Shop around the Corner | 1940 | Ernst Lubitsch |
| 1980 | The Shop on Main Street | 1965 | Ján Kadár and Elmar Klos |
| 1082 | Shoplifters | 2018 | Hirokazu Koreeda |
| 1032 | Short Cuts | 1993 | Robert Altman |
| 1957 | A Short Film about Killing | 1988 | Krzysztof Kieslowski |
| 2148 | A Short Film about Love | 1988 | Krzysztof Kieslowski |
| 2667 | Short Term 12 | 2013 | Destin Daniel Cretton |
| 2237 | Shortbus | 2006 | John Cameron Mitchell |
| 1525 | A Shot in the Dark | 1964 | Blake Edwards |
| 2453 | Show Boat | 1936 | James Whale |
| 1373 | Show Me Love | 1998 | Lukas Moodysson |
| 2532 | Show People | 1928 | King Vidor |
| 1378 | Showgirls | 1995 | Paul Verhoeven |
| 338 | Shrek | 2001 | Andrew Adamson and Vicky Jenson |
| 1114 | Shrek 2 | 2004 | Andrew Adamson, Kelly Asbury, and Conrad Vernon |
| 638 | Shutter Island | 2010 | Martin Scorsese |
