| Rank | Title | Year | Director(s) |
| 1416 | Saboteur | 1942 | Alfred Hitchcock |
| 1059 | Sabrina | 1954 | Billy Wilder |
| 754 | Safe | 1995 | Todd Haynes |
| 672 | Safety Last! | 1923 | Fred C. Newmeyer and Sam Taylor |
| 1719 | Salaam Bombay! | 1988 | Mira Nair |
| 878 | Salesman | 1968 | Albert and David Maysles and Charlotte Zwerin |
| 1310 | Salň | 1975 | Pier Paolo Pasolini |
| 1550 | Salt of the Earth | 1954 | Herbert J. Biberman |
| 1349 | Salvador | 1986 | Oliver Stone |
| 1737 | Salvatore Giuliano | 1962 | Francesco Rosi |
| 504 | Le Samouraď | 1967 | Jean-Pierre Melville |
| 2255 | Samson and Delilah | 1949 | Cecil B. DeMille |
| 2212 | Samurai 1: Musashi Miyamoto | 1954 | Hiroshi Inagaki |
| 1854 | San Francisco | 1936 | W.S. Van Dyke |
| 1418 | Sands of Iwo Jima | 1949 | Allan Dwan |
| 1033 | Sans soleil | 1983 | Chris Marker |
| 464 | Sansho the Bailiff | 1954 | Kenji Mizoguchi |
| 1155 | Sátántangó | 1994 | Béla Tarr |
| 772 | Saturday Night and Sunday Morning | 1960 | Karel Reisz |
| 360 | Saturday Night Fever | 1977 | John Badham |
| 50 | Saving Private Ryan | 1998 | Steven Spielberg |
| 1534 | Saw | 2004 | James Wan |
| 448 | Say Anything… | 1989 | Cameron Crowe |
| 2183 | A Scanner Darkly | 2006 | Richard Linklater |
| 328 | Scarface | 1932 | Howard Hawks |
| 239 | Scarface | 1983 | Brian De Palma |
| 631 | The Scarlet Empress | 1934 | Josef von Sternberg |
| 1870 | Scarlet Street | 1945 | Fritz Lang |
| 979 | Scenes from a Marriage | 1973 | Ingmar Bergman |
| 1753 | Scent of a Woman | 1992 | Martin Brest |
| 22 | Schindler's List | 1993 | Steven Spielberg |
| 2261 | Schizopolis | 1996 | Steven Soderbergh |
| 1294 | The School of Rock | 2003 | Richard Linklater |
| 1791 | Scorpio Rising | 1964 | Kenneth Anger |
| 324 | Scream | 1996 | Wes Craven |
| 1726 | Scream 2 | 1997 | Wes Craven |
| 962 | Scrooge | 1951 | Brian Desmond Hurst |
| 1702 | The Sea Hawk | 1940 | Michael Curtiz |
| 1431 | The Sea Inside | 2004 | Alejandro Amenábar |
| 1610 | Seabiscuit | 2003 | Gary Ross |
| 2385 | The Search | 1948 | Fred Zinnemann |
| 28 | The Searchers | 1956 | John Ford |
| 1149 | Searching for Bobby Fischer | 1993 | Steven Zaillian |
| 1122 | Seconds | 1966 | John Frankenheimer |
| 2050 | The Secret Garden | 1993 | Agnieszka Holland |
| 1859 | The Secret of NIMH | 1982 | Don Bluth |
| 1814 | The Secret of Roan Inish | 1994 | John Sayles |
| 1271 | Secretary | 2002 | Steven Shainberg |
| 389 | Secrets & Lies | 1996 | Mike Leigh |
| 2170 | Selena | 1997 | Gregory Nava |
| 405 | Sense and Sensibility | 1995 | Ang Lee |
| 1346 | Senso | 1954 | Luchino Visconti |
| 893 | Serenity | 2005 | Joss Whedon |
| 919 | Sergeant York | 1941 | Howard Hawks |
| 1057 | Serpico | 1973 | Sidney Lumet |
| 688 | The Servant | 1963 | Joseph Losey |
| 1275 | The Set-Up | 1949 | Robert Wise |
| 112 | Seven | 1995 | David Fincher |
| 1049 | Seven Beauties | 1975 | Lina Wertmüller |
| 580 | Seven Brides for Seven Brothers | 1954 | Stanley Donen |
| 2125 | Seven Chances | 1925 | Buster Keaton |
| 1717 | Seven Days in May | 1964 | John Frankenheimer |
| 1345 | Seven Men from Now | 1956 | Budd Boetticher |
| 32 | The Seven Samurai | 1954 | Akira Kurosawa |
| 2318 | Seven Up! | 1964 | Paul Almond |
| 817 | The Seven Year Itch | 1955 | Billy Wilder |
| 2282 | Seventh Heaven | 1927 | Frank Borzage |
| 119 | The Seventh Seal | 1957 | Ingmar Bergman |
| 520 | Sex, Lies, and Videotape | 1989 | Steven Soderbergh |
| 920 | Sexy Beast | 2000 | Jonathan Glazer |
| 382 | Shadow of a Doubt | 1943 | Alfred Hitchcock |
| 1744 | Shadowlands | 1993 | Richard Attenborough |
| 611 | Shadows | 1959 | John Cassavetes |
| 1551 | Shadows of Forgotten Ancestors | 1965 | Sergei Parajanov |
| 746 | Shaft | 1971 | Gordon Parks |
| 244 | Shakespeare in Love | 1998 | John Madden |
| 1918 | Shall We Dance | 1937 | Mark Sandrich |
| 1864 | Shall We Dance? | 1996 | Masayuki Suo |
| 1023 | Shallow Grave | 1994 | Danny Boyle |
| 1585 | Shame | 1968 | Ingmar Bergman |
| 1200 | Shampoo | 1975 | Hal Ashby |
| 200 | Shane | 1953 | George Stevens |
| 1457 | Shanghai Express | 1932 | Josef von Sternberg |
| 394 | Shaun of the Dead | 2004 | Edgar Wright |
| 46 | The Shawshank Redemption | 1994 | Frank Darabont |
| 1278 | She Done Him Wrong | 1933 | Lowell Sherman |
| 1098 | She Wore a Yellow Ribbon | 1949 | John Ford |
| 2033 | The Sheik | 1921 | George Melford |
| 261 | Sherlock, Jr. | 1924 | Buster Keaton |
| 1529 | Sherman's March | 1986 | Ross McElwee |
| 912 | She's Gotta Have It | 1986 | Spike Lee |
| 1022 | Shine | 1996 | Scott Hicks |
| 87 | The Shining | 1980 | Stanley Kubrick |
| 2019 | Shivers | 1975 | David Cronenberg |
| 415 | Shoah | 1985 | Claude Lanzmann |
| 849 | Shock Corridor | 1963 | Samuel Fuller |
| 1524 | Shoeshine | 1946 | Vittorio De Sica |
| 1987 | Sholay | 1975 | Ramesh Sippy |
| 699 | Shoot the Piano Player | 1960 | François Truffaut |
| 1512 | The Shootist | 1976 | Don Siegel |
| 472 | The Shop around the Corner | 1940 | Ernst Lubitsch |
| 956 | The Shop on Main Street | 1965 | Ján Kadár and Elmar Klos |
| 603 | Short Cuts | 1993 | Robert Altman |
| 1506 | A Short Film about Killing | 1988 | Krzysztof Kieslowski |
| 861 | A Shot in the Dark | 1964 | Blake Edwards |
| 1205 | Show Boat | 1936 | James Whale |
| 2052 | Show Me Love | 1998 | Lukas Moodysson |
| 1293 | Showgirls | 1995 | Paul Verhoeven |
| 284 | Shrek | 2001 | Andrew Adamson and Vicky Jenson |
| 1380 | Shrek 2 | 2004 | Andrew Adamson, Kelly Asbury, and Conrad Vernon |
