| Rank | Title | Year | Director(s) |
| 2257 | Sabotage | 1936 | Alfred Hitchcock |
| 2562 | Saboteur | 1942 | Alfred Hitchcock |
| 1394 | Sabrina | 1954 | Billy Wilder |
| 987 | The Sacrifice | 1986 | Andrei Tarkovsky |
| 1021 | Safe | 1995 | Todd Haynes |
| 658 | Safety Last! | 1923 | Fred C. Newmeyer and Sam Taylor |
| 1842 | Salaam Bombay! | 1988 | Mira Nair |
| 906 | Salesman | 1969 | Albert and David Maysles and Charlotte Zwerin |
| 928 | Salň | 1975 | Pier Paolo Pasolini |
| 2572 | Salt of the Earth | 1954 | Herbert J. Biberman |
| 1820 | Salvador | 1986 | Oliver Stone |
| 2068 | Salvatore Giuliano | 1962 | Francesco Rosi |
| 375 | Le Samouraď | 1967 | Jean-Pierre Melville |
| 1861 | Samurai Rebellion | 1967 | Masaki Kobayashi |
| 1206 | The Sandlot | 1993 | David M. Evans |
| 2376 | Sands of Iwo Jima | 1949 | Allan Dwan |
| 2394 | Le Sang des bętes | 1949 | Georges Franju |
| 1921 | Sanjuro | 1962 | Akira Kurosawa |
| 561 | Sans soleil | 1983 | Chris Marker |
| 376 | Sansho the Bailiff | 1954 | Kenji Mizoguchi |
| 2596 | Santa Sangre | 1989 | Alejandro Jodorowsky |
| 2291 | The Saragossa Manuscript | 1965 | Wojciech Has |
| 650 | Sátántangó | 1994 | Béla Tarr |
| 982 | Saturday Night and Sunday Morning | 1960 | Karel Reisz |
| 587 | Saturday Night Fever | 1977 | John Badham |
| 2644 | Saved! | 2004 | Brian Dannelly |
| 77 | Saving Private Ryan | 1998 | Steven Spielberg |
| 1158 | Saw | 2004 | James Wan |
| 526 | Say Anything… | 1989 | Cameron Crowe |
| 1389 | A Scanner Darkly | 2006 | Richard Linklater |
| 2121 | Scanners | 1981 | David Cronenberg |
| 202 | Scarface | 1983 | Brian De Palma |
| 534 | Scarface | 1932 | Howard Hawks |
| 913 | The Scarlet Empress | 1934 | Josef von Sternberg |
| 1513 | Scarlet Street | 1945 | Fritz Lang |
| 950 | Scenes from a Marriage | 1974 | Ingmar Bergman |
| 1260 | Scent of a Woman | 1992 | Martin Brest |
| 28 | Schindler's List | 1993 | Steven Spielberg |
| 1256 | The School of Rock | 2003 | Richard Linklater |
| 1122 | Scorpio Rising | 1963 | Kenneth Anger |
| 1330 | Scott Pilgrim vs. the World | 2010 | Edgar Wright |
| 527 | Scream | 1996 | Wes Craven |
| 1914 | Scrooge | 1951 | Brian Desmond Hurst |
| 2778 | The Sea Hawk | 1940 | Michael Curtiz |
| 1232 | The Sea Inside | 2004 | Alejandro Amenábar |
| 1474 | Seabiscuit | 2003 | Gary Ross |
| 37 | The Searchers | 1956 | John Ford |
| 1905 | Searching for Sugar Man | 2012 | Malik Mendjelloul |
| 817 | Seconds | 1966 | John Frankenheimer |
| 2237 | The Secret Garden | 1993 | Agnieszka Holland |
| 1455 | The Secret in Their Eyes | 2009 | Juan José Campanella |
| 1999 | The Secret of Kells | 2009 | Tomm Moore |
| 1203 | The Secret of NIMH | 1982 | Don Bluth |
| 1424 | Secretary | 2002 | Steven Shainberg |
| 470 | Secrets & Lies | 1996 | Mike Leigh |
| 1589 | Selma | 2014 | Ava DuVernay |
| 1127 | Senna | 2010 | Asif Kapadia |
| 602 | Sense and Sensibility | 1995 | Ang Lee |
| 1364 | Senso | 1954 | Luchino Visconti |
| 747 | A Separation | 2011 | Asghar Farhadi |
| 891 | Serenity | 2005 | Joss Whedon |
| 1133 | Sergeant York | 1941 | Howard Hawks |
| 1387 | A Serious Man | 2009 | Ethan and Joel Coen |
| 767 | Serpico | 1973 | Sidney Lumet |
| 824 | The Servant | 1963 | Joseph Losey |
| 2319 | Session 9 | 2001 | Brad Anderson |
| 1437 | The Set-Up | 1949 | Robert Wise |
| 102 | Seven | 1995 | David Fincher |
| 1721 | Seven Beauties | 1975 | Lina Wertmüller |
| 1169 | Seven Brides for Seven Brothers | 1954 | Stanley Donen |
| 1840 | Seven Chances | 1925 | Buster Keaton |
| 2018 | Seven Days in May | 1964 | John Frankenheimer |
| 1201 | Seven Men from Now | 1956 | Budd Boetticher |
| 1431 | Seven Plus Seven | 1970 | Michael Apted |
| 22 | Seven Samurai | 1954 | Akira Kurosawa |
| 1196 | Seven Up! | 1964 | Paul Almond |
| 1425 | The Seven Year Itch | 1955 | Billy Wilder |
| 1928 | Seventh Heaven | 1927 | Frank Borzage |
| 93 | The Seventh Seal | 1957 | Ingmar Bergman |
| 2351 | The Seventh Victim | 1943 | Mark Robson |
| 582 | Sex, Lies, and Videotape | 1989 | Steven Soderbergh |
| 941 | Sexy Beast | 2000 | Jonathan Glazer |
| 432 | Shadow of a Doubt | 1943 | Alfred Hitchcock |
| 460 | Shadows | 1958 | John Cassavetes |
| 1671 | Shadows of Forgotten Ancestors | 1965 | Sergei Parajanov |
| 993 | Shaft | 1971 | Gordon Parks |
| 592 | Shakespeare in Love | 1998 | John Madden |
| 2537 | Shallow Grave | 1994 | Danny Boyle |
| 2787 | Shame | 2011 | Steve McQueen |
| 2355 | Shame | 1968 | Ingmar Bergman |
| 1871 | Shampoo | 1975 | Hal Ashby |
| 341 | Shane | 1953 | George Stevens |
| 1741 | Shanghai Express | 1932 | Josef von Sternberg |
| 1990 | Shaolin Soccer | 2001 | Stephen Chow |
| 2064 | The Shape of Water | 2017 | Guillermo del Toro |
| 260 | Shaun of the Dead | 2004 | Edgar Wright |
| 52 | The Shawshank Redemption | 1994 | Frank Darabont |
| 2069 | She Done Him Wrong | 1933 | Lowell Sherman |
| 1009 | She Wore a Yellow Ribbon | 1949 | John Ford |
| 2528 | Sherlock Holmes | 2009 | Guy Ritchie |
| 198 | Sherlock, Jr. | 1924 | Buster Keaton |
| 1266 | Sherman's March | 1985 | Ross McElwee |
| 1537 | She's Gotta Have It | 1986 | Spike Lee |
| 1838 | Shine | 1996 | Scott Hicks |
| 41 | The Shining | 1980 | Stanley Kubrick |
| 2366 | Shivers | 1975 | David Cronenberg |
| 243 | Shoah | 1985 | Claude Lanzmann |
| 1060 | Shock Corridor | 1963 | Samuel Fuller |
| 1715 | Shoeshine | 1946 | Vittorio De Sica |
| 2266 | Sholay | 1975 | Ramesh Sippy |
| 807 | Shoot the Piano Player | 1960 | François Truffaut |
| 1958 | The Shooting | 1966 | Monte Hellman |
| 1110 | The Shootist | 1976 | Don Siegel |
| 345 | The Shop around the Corner | 1940 | Ernst Lubitsch |
| 1121 | The Shop on Main Street | 1965 | Ján Kadár and Elmar Klos |
| 675 | Short Cuts | 1993 | Robert Altman |
| 1522 | A Short Film about Killing | 1988 | Krzysztof Kieslowski |
| 2046 | A Short Film about Love | 1988 | Teresa Violetta Buhl, Krzysztof Kieslowski, and Pawel Rzepkowski |
| 2419 | Shortbus | 2006 | John Cameron Mitchell |
| 1544 | A Shot in the Dark | 1964 | Blake Edwards |
| 2083 | Show Boat | 1936 | James Whale |
| 1443 | Show Me Love | 1998 | Lukas Moodysson |
| 2500 | Show People | 1928 | King Vidor |
| 1634 | Showgirls | 1995 | Paul Verhoeven |
| 353 | Shrek | 2001 | Andrew Adamson and Vicky Jenson |
| 1287 | Shrek 2 | 2004 | Andrew Adamson, Kelly Asbury, and Conrad Vernon |
| 2751 | Shut Up & Sing | 2006 | Barbara Kopple and Cecilia Peck |
| 1083 | Shutter Island | 2010 | Martin Scorsese |
