| Rank | Title | Year | Director(s) |
| 2427 | Sicko | 2007 | Michael Moore |
| 1889 | Sid and Nancy | 1986 | Alex Cox |
| 606 | Sideways | 2004 | Alexander Payne |
| 1195 | Siegfried | 1924 | Fritz Lang |
| 2007 | Signs | 2002 | M. Night Shyamalan |
| 31 | The Silence of the Lambs | 1991 | Jonathan Demme |
| 1318 | The Silence | 1963 | Ingmar Bergman |
| 1056 | Silent Running | 1972 | Douglas Trumbull |
| 1924 | Silkwood | 1983 | Mike Nichols |
| 1441 | Silver Linings Playbook | 2012 | David O. Russell |
| 2791 | Silver Streak | 1976 | Arthur Hiller |
| 1839 | Silverado | 1985 | Lawrence Kasdan |
| 2523 | A Simple Plan | 1998 | Sam Raimi |
| 2711 | The Simpsons Movie | 2007 | David Silverman |
| 515 | Sin City | 2005 | Frank Miller and Robert Rodriguez |
| 7 | Singin' in the Rain | 1952 | Stanley Donen and Gene Kelly |
| 2087 | A Single Man | 2009 | Tom Ford |
| 2587 | Sisters | 1972 | Brian De Palma |
| 2676 | Sita Sings the Blues | 2008 | Nina Paley |
| 1057 | Sixteen Candles | 1984 | John Hughes |
| 187 | The Sixth Sense | 1999 | M. Night Shyamalan |
| 2244 | The Skin I Live In | 2011 | Pedro Almodóvar |
| 1259 | Skyfall | 2012 | Sam Mendes |
| 1207 | Slacker | 1990 | Richard Linklater |
| 801 | Slap Shot | 1977 | George Roy Hill |
| 2286 | Slaughterhouse-Five | 1972 | George Roy Hill |
| 499 | Sleeper | 1973 | Woody Allen |
| 2533 | Sleepers | 1996 | Barry Levinson |
| 974 | Sleeping Beauty | 1959 | Clyde Geronimi |
| 738 | Sleepless in Seattle | 1993 | Nora Ephron |
| 1764 | Sleepy Hollow | 1999 | Tim Burton |
| 1430 | Sleuth | 1972 | Joseph L. Mankiewicz |
| 1165 | Sling Blade | 1996 | Billy Bob Thornton |
| 394 | Slumdog Millionaire | 2008 | Danny Boyle |
| 1108 | Smiles of a Summer Night | 1955 | Ingmar Bergman |
| 2595 | The Smiling Madame Beudet | 1923 | Germaine Dulac |
| 2273 | Smoke | 1995 | Wayne Wang |
| 2792 | Smokey and the Bandit | 1977 | Hal Needham |
| 673 | Snatch. | 2000 | Guy Ritchie |
| 104 | Snow White and the Seven Dwarfs | 1937 | David Hand |
| 2380 | Snowpiercer | 2013 | Bong Joon Ho |
| 514 | The Social Network | 2010 | David Fincher |
| 2798 | Society | 1989 | Brian Yuzna |
| 2161 | Solaris | 2002 | Steven Soderbergh |
| 227 | Solaris | 1972 | Andrei Tarkovsky |
| 1891 | Some Came Running | 1958 | Vincente Minnelli |
| 10 | Some Like It Hot | 1959 | Billy Wilder |
| 2086 | Something Wild | 1986 | Jonathan Demme |
| 2498 | Son of Saul | 2015 | László Nemes |
| 1852 | The Son | 2002 | Jean-Pierre and Luc Dardenne |
| 1726 | Sonatine | 1993 | Takeshi Kitano |
| 2345 | Song of the Sea | 2014 | Tomm Moore |
| 1982 | Songs from the Second Floor | 2000 | Roy Andersson |
| 1066 | Sons of the Desert | 1933 | William A. Seiter |
| 2545 | The Son's Room | 2001 | Nanni Moretti |
| 1152 | Sophie's Choice | 1982 | Alan J. Pakula |
| 1747 | Sorcerer | 1977 | William Friedkin |
| 2384 | Il Sorpasso | 1962 | Dino Risi |
| 709 | The Sorrow and the Pity | 1969 | Marcel Ophüls |
| 144 | The Sound of Music | 1965 | Robert Wise |
| 2154 | Sounder | 1972 | Martin Ritt |
| 2143 | South Pacific | 1958 | Joshua Logan |
| 407 | South Park: Bigger Longer & Uncut | 1999 | Trey Parker |
| 1040 | Soylent Green | 1973 | Richard Fleischer |
| 2525 | Space Jam | 1996 | Joe Pytka |
| 1931 | Spaceballs | 1987 | Mel Brooks |
| 254 | Spartacus | 1960 | Stanley Kubrick |
| 1835 | A Special Day | 1977 | Ettore Scola |
| 473 | Speed | 1994 | Jan de Bont |
| 1351 | Spellbound | 2002 | Jeffrey Blitz |
| 1987 | Spellbound | 1945 | Alfred Hitchcock |
| 655 | Spider-Man | 2002 | Sam Raimi |
| 652 | Spider-Man 2 | 2004 | Sam Raimi |
| 1118 | Spider-Man: Into the Spider-Verse | 2018 | Bob Persichett, Peter Ramsey, and Rodney Rothman |
| 2201 | Spione | 1928 | Fritz Lang |
| 2425 | The Spiral Staircase | 1946 | Robert Siodmak |
| 352 | The Spirit of the Beehive | 1973 | Víctor Erice |
| 79 | Spirited Away | 2001 | Hayao Miyazaki |
| 2476 | Splash | 1984 | Ron Howard |
| 1233 | Splendor in the Grass | 1961 | Elia Kazan |
| 1373 | Spotlight | 2015 | Tom McCarthy |
| 2354 | Spring in a Small Town | 1948 | Mu Fei |
| 1098 | Spring, Summer, Fall, Winter... and Spring | 2003 | Ki-duk Kim |
| 1984 | The Spy Who Came in from the Cold | 1965 | Martin Ritt |
| 2017 | The Spy Who Loved Me | 1977 | Lewis Gilbert |
| 1696 | The Squid and the Whale | 2005 | Noah Baumbach |
| 2186 | Stage Door | 1937 | Gregory La Cava |
| 140 | Stagecoach | 1939 | John Ford |
| 240 | Stairway to Heaven | 1946 | Michael Powell and Emeric Pressburger |
| 633 | Stalag 17 | 1953 | Billy Wilder |
| 2679 | Stalingrad | 1993 | Joseph Vilsmaier |
| 222 | Stalker | 1979 | Andrei Tarkovsky |
| 325 | Stand by Me | 1986 | Rob Reiner |
| 396 | A Star Is Born | 1954 | George Cukor |
| 623 | Star Trek | 2009 | J.J. Abrams |
| 2089 | Star Trek into Darkness | 2013 | J.J. Abrams |
| 1973 | Star Trek IV: The Voyage Home | 1986 | Leonard Nimoy |
| 2468 | Star Trek VI: The Undiscovered Country | 1991 | Nicholas Meyer |
| 1672 | Star Trek: First Contact | 1996 | Jonathan Frakes |
| 393 | Star Trek: The Wrath of Khan | 1982 | Nicholas Meyer |
| 6 | Star Wars | 1977 | George Lucas |
| 2263 | Star Wars: Episode I - The Phantom Menace | 1999 | George Lucas |
| 1139 | Star Wars: Episode III - Revenge of the Sith | 2005 | George Lucas |
| 925 | Star Wars: Episode VII - The Force Awakens | 2015 | J.J. Abrams |
| 2072 | Star Wars: Episode VIII - The Last Jedi | 2017 | Rian Johnson |
| 2126 | Stardust | 2007 | Matthew Vaughn |
| 2269 | Stardust Memories | 1980 | Woody Allen |
| 2739 | Stargate | 1994 | Roland Emmerich |
| 2074 | Starman | 1984 | John Carpenter |
| 549 | Starship Troopers | 1997 | Paul Verhoeven |
| 1825 | The Station Agent | 2003 | Tom McCarthy |
| 781 | Steamboat Bill, Jr. | 1928 | Charles Reisner |
| 1819 | The Steel Helmet | 1951 | Samuel Fuller |
| 1658 | Steel Magnolias | 1989 | Herbert Ross |
| 1913 | Stella Dallas | 1937 | King Vidor |
| 2290 | Step Brothers | 2008 | Adam McKay |
| 2465 | Still Life | 2006 | Zhangke Jia |
| 294 | The Sting | 1973 | George Roy Hill |
| 2629 | Stir Crazy | 1980 | Sidney Poitier |
| 1860 | Stolen Kisses | 1968 | François Truffaut |
| 700 | Stop Making Sense | 1984 | Jonathan Demme |
| 1722 | Stories We Tell | 2012 | Sarah Polley |
| 2204 | Stormy Weather | 1943 | Andrew L. Stone |
| 2448 | The Story of a Cheat | 1936 | Sacha Guitry |
| 1162 | The Story of the Late Chrysanthemums | 1939 | Kenji Mizoguchi |
| 276 | La Strada | 1954 | Federico Fellini |
| 916 | The Straight Story | 1999 | David Lynch |
| 1417 | Strange Days | 1995 | Kathryn Bigelow |
| 2443 | Stranger by the Lake | 2013 | Alain Guiraudie |
| 578 | Stranger than Paradise | 1984 | Jim Jarmusch |
| 263 | Strangers on a Train | 1951 | Alfred Hitchcock |
| 915 | Straw Dogs | 1971 | Sam Peckinpah |
| 1965 | Stray Dog | 1949 | Akira Kurosawa |
| 196 | A Streetcar Named Desire | 1951 | Elia Kazan |
| 2059 | Strictly Ballroom | 1992 | Baz Luhrmann |
| 1176 | Strike | 1925 | Sergei M. Eisenstein |
| 2003 | Stripes | 1981 | Ivan Reitman |
| 2132 | Stromboli | 1950 | Roberto Rossellini |
| 2138 | Stroszek | 1977 | Werner Herzog |
| 2267 | The Stunt Man | 1980 | Richard Rush |
| 2316 | Sugar | 2008 | Anna Boden and Ryan Fleck |
| 252 | Sullivan's Travels | 1941 | Preston Sturges |
| 1778 | Summer | 1986 | Eric Rohmer |
| 2211 | Sunday Bloody Sunday | 1971 | John Schlesinger |
| 81 | Sunrise | 1927 | F.W. Murnau |
| 25 | Sunset Blvd. | 1950 | Billy Wilder |
| 1438 | Sunshine | 2007 | Danny Boyle |
| 1830 | Super Fly | 1972 | Gordon Parks Jr. |
| 1827 | Super Size Me | 2004 | Morgan Spurlock |
| 777 | Superbad | 2007 | Greg Mottola |
| 2180 | Supercop | 1992 | Stanley Tong |
| 275 | Superman | 1978 | Richard Donner |
| 971 | Superman II | 1980 | Richard Lester |
| 2374 | Superstar: The Karen Carpenter Story | 1988 | Todd Haynes |
| 2494 | El Sur | 1983 | Víctor Erice |
| 2393 | The Sure Thing | 1985 | Rob Reiner |
| 2312 | Suspicion | 1941 | Alfred Hitchcock |
| 302 | Suspiria | 1977 | Dario Argento |
| 1006 | Sweeney Todd: The Demon Barber of Fleet Street | 2007 | Tim Burton |
| 1025 | The Sweet Hereafter | 1997 | Atom Egoyan |
| 173 | Sweet Smell of Success | 1957 | Alexander Mackendrick |
| 730 | Sweet Sweetback's Baadasssss Song | 1971 | Melvin Van Peebles |
| 2700 | Swept Away ... by an Unusual Destiny in the Blue Sea of August | 1974 | Lina Wertmüller |
| 2219 | The Swimmer | 1968 | Frank Perry |
| 772 | Swing Time | 1936 | George Stevens |
| 1103 | Swingers | 1996 | Doug Liman |
| 2349 | Sympathy for Mr. Vengeance | 2002 | Chan-wook Park |
| 1123 | Synecdoche, New York | 2008 | Charlie Kaufman |
