| Rank | Title | Year | Director(s) |
| 1362 | Sicario | 2015 | Denis Villeneuve |
| 2779 | Sicko | 2007 | Michael Moore |
| 2241 | Sid and Nancy | 1986 | Alex Cox |
| 742 | Sideways | 2004 | Alexander Payne |
| 1622 | Siegfried | 1924 | Fritz Lang |
| 1581 | Signs | 2002 | M. Night Shyamalan |
| 2874 | Silence | 2016 | Martin Scorsese |
| 20 | The Silence of the Lambs | 1991 | Jonathan Demme |
| 1718 | The Silence | 1963 | Ingmar Bergman |
| 1117 | Silent Running | 1972 | Douglas Trumbull |
| 2112 | Silkwood | 1983 | Mike Nichols |
| 915 | Silver Linings Playbook | 2012 | David O. Russell |
| 1881 | Silverado | 1985 | Lawrence Kasdan |
| 2587 | A Simple Plan | 1998 | Sam Raimi |
| 2884 | The Simpsons Movie | 2007 | David Silverman |
| 737 | Sin City | 2005 | Frank Miller and Robert Rodriguez |
| 2084 | Sing Street | 2016 | John Carney |
| 7 | Singin' in the Rain | 1952 | Stanley Donen and Gene Kelly |
| 1839 | A Single Man | 2009 | Tom Ford |
| 2618 | Singles | 1992 | Cameron Crowe |
| 2047 | Sisters | 1972 | Brian De Palma |
| 2289 | Sita Sings the Blues | 2008 | Nina Paley |
| 1389 | Sixteen Candles | 1984 | John Hughes |
| 168 | The Sixth Sense | 1999 | M. Night Shyamalan |
| 1516 | The Skin I Live In | 2011 | Pedro Almodóvar |
| 703 | Skyfall | 2012 | Sam Mendes |
| 1577 | Slacker | 1990 | Richard Linklater |
| 841 | Slap Shot | 1977 | George Roy Hill |
| 2971 | Slaughterhouse-Five | 1972 | George Roy Hill |
| 3049 | Sleepaway Camp | 1983 | Robert Hiltzik |
| 628 | Sleeper | 1973 | Woody Allen |
| 2982 | Sleepers | 1996 | Barry Levinson |
| 847 | Sleeping Beauty | 1959 | Clyde Geronimi |
| 586 | Sleepless in Seattle | 1993 | Nora Ephron |
| 1441 | Sleepy Hollow | 1999 | Tim Burton |
| 1747 | Sleuth | 1972 | Joseph L. Mankiewicz |
| 1175 | Sling Blade | 1996 | Billy Bob Thornton |
| 403 | Slumdog Millionaire | 2008 | Danny Boyle |
| 1663 | Smiles of a Summer Night | 1955 | Ingmar Bergman |
| 2866 | The Smiling Madame Beudet | 1923 | Germaine Dulac |
| 2947 | Smoke | 1995 | Wayne Wang |
| 645 | Snatch. | 2000 | Guy Ritchie |
| 115 | Snow White and the Seven Dwarfs | 1937 | David Hand |
| 831 | Snowpiercer | 2013 | Bong Joon Ho |
| 301 | The Social Network | 2010 | David Fincher |
| 2915 | Society | 1989 | Brian Yuzna |
| 170 | Solaris | 1972 | Andrei Tarkovsky |
| 2025 | Some Came Running | 1958 | Vincente Minnelli |
| 19 | Some Like It Hot | 1959 | Billy Wilder |
| 2465 | Something Wild | 1986 | Jonathan Demme |
| 1470 | Something's Gotta Give | 2003 | Nancy Meyers |
| 2656 | The Son | 2002 | Jean-Pierre and Luc Dardenne |
| 1320 | Son of Saul | 2015 | László Nemes |
| 2429 | Sonatine | 1993 | Takeshi Kitano |
| 1570 | Song of the Sea | 2014 | Tomm Moore |
| 1976 | Songs from the Second Floor | 2000 | Roy Andersson |
| 1645 | Sons of the Desert | 1933 | William A. Seiter |
| 1075 | Sophie's Choice | 1982 | Alan J. Pakula |
| 1550 | Sorcerer | 1977 | William Friedkin |
| 2228 | Il Sorpasso | 1962 | Dino Risi |
| 766 | The Sorrow and the Pity | 1969 | Marcel Ophüls |
| 1975 | Sorry to Bother You | 2018 | Boots Riley |
| 1130 | Soul | 2020 | Pete Docter |
| 135 | The Sound of Music | 1965 | Robert Wise |
| 1897 | Sounder | 1972 | Martin Ritt |
| 2499 | Source Code | 2011 | Duncan Jones |
| 578 | South Park: Bigger Longer & Uncut | 1999 | Trey Parker |
| 2908 | The Souvenir | 2019 | Joanna Hogg |
| 1061 | Soylent Green | 1973 | Richard Fleischer |
| 1765 | Space Jam | 1996 | Joe Pytka |
| 2154 | Spaceballs | 1987 | Mel Brooks |
| 336 | Spartacus | 1960 | Stanley Kubrick |
| 1814 | A Special Day | 1977 | Ettore Scola |
| 547 | Speed | 1994 | Jan de Bont |
| 2097 | Spellbound | 2002 | Jeffrey Blitz |
| 2099 | Spellbound | 1945 | Alfred Hitchcock |
| 516 | Spider-Man | 2002 | Sam Raimi |
| 459 | Spider-Man 2 | 2004 | Sam Raimi |
| 1292 | Spider-Man: Across the Spider-Verse | 2023 | Joaquim Dos Santos, Kemp Powers, and Justin K. Thompson |
| 2433 | Spider-Man: Far from Home | 2019 | Jon Watts |
| 1159 | Spider-Man: Homecoming | 2017 | Jon Watts |
| 189 | Spider-Man: Into the Spider-Verse | 2018 | Bob Persichett, Peter Ramsey, and Rodney Rothman |
| 1494 | Spider-Man: No Way Home | 2021 | Jon Watts |
| 2784 | The Spiral Staircase | 1946 | Robert Siodmak |
| 390 | The Spirit of the Beehive | 1973 | Víctor Erice |
| 32 | Spirited Away | 2001 | Hayao Miyazaki |
| 2208 | Splash | 1983 | Ron Howard |
| 1189 | Splendor in the Grass | 1961 | Elia Kazan |
| 783 | Spotlight | 2015 | Tom McCarthy |
| 1952 | Spring in a Small Town | 1948 | Mu Fei |
| 1064 | Spring, Summer, Fall, Winter... and Spring | 2003 | Kim Ki-duk |
| 2506 | Spy | 2015 | Paul Feig |
| 2624 | The Spy Who Came in from the Cold | 1965 | Martin Ritt |
| 1660 | The Spy Who Loved Me | 1977 | Lewis Gilbert |
| 2202 | The Squid and the Whale | 2005 | Noah Baumbach |
| 2985 | Stage Door | 1937 | Gregory La Cava |
| 183 | Stagecoach | 1939 | John Ford |
| 544 | Stalag 17 | 1953 | Billy Wilder |
| 2988 | Stalingrad | 1993 | Joseph Vilsmaier |
| 195 | Stalker | 1979 | Andrei Tarkovsky |
| 307 | Stand by Me | 1986 | Rob Reiner |
| 453 | A Star Is Born | 1954 | George Cukor |
| 1364 | A Star Is Born | 2018 | Bradley Cooper |
| 522 | Star Trek | 2009 | J.J. Abrams |
| 1613 | Star Trek into Darkness | 2013 | J.J. Abrams |
| 2068 | Star Trek IV: The Voyage Home | 1986 | Leonard Nimoy |
| 2771 | Star Trek VI: The Undiscovered Country | 1991 | Nicholas Meyer |
| 1327 | Star Trek: First Contact | 1996 | Jonathan Frakes |
| 2706 | Star Trek: The Motion Picture | 1979 | Robert Wise |
| 317 | Star Trek: The Wrath of Khan | 1982 | Nicholas Meyer |
| 4 | Star Wars | 1977 | George Lucas |
| 2013 | Star Wars: Episode I - The Phantom Menace | 1999 | George Lucas |
| 2335 | Star Wars: Episode II - Attack of the Clones | 2002 | George Lucas |
| 887 | Star Wars: Episode III - Revenge of the Sith | 2005 | George Lucas |
| 565 | Star Wars: Episode VII - The Force Awakens | 2015 | J.J. Abrams |
| 938 | Star Wars: Episode VIII - The Last Jedi | 2017 | Rian Johnson |
| 1667 | Stardust | 2007 | Matthew Vaughn |
| 2373 | Starman | 1984 | John Carpenter |
| 596 | Starship Troopers | 1997 | Paul Verhoeven |
| 2193 | The Station Agent | 2003 | Tom McCarthy |
| 974 | Steamboat Bill, Jr. | 1928 | Charles Reisner |
| 1909 | The Steel Helmet | 1951 | Samuel Fuller |
| 1415 | Steel Magnolias | 1989 | Herbert Ross |
| 2022 | Stella Dallas | 1937 | King Vidor |
| 1832 | Step Brothers | 2008 | Adam McKay |
| 2794 | Stepmom | 1998 | Chris Columbus |
| 2313 | Still Life | 2006 | Jia Zhang-ke |
| 1862 | Still Walking | 2008 | Hirokazu Koreeda |
| 343 | The Sting | 1973 | George Roy Hill |
| 1893 | Stolen Kisses | 1968 | François Truffaut |
| 622 | Stop Making Sense | 1984 | Jonathan Demme |
| 1277 | Stories We Tell | 2012 | Sarah Polley |
| 2076 | Stormy Weather | 1943 | Andrew L. Stone |
| 3006 | Story of G.I. Joe | 1945 | William A. Wellman |
| 1631 | The Story of the Late Chrysanthemums | 1939 | Kenji Mizoguchi |
| 366 | La Strada | 1954 | Federico Fellini |
| 1986 | Straight Outta Compton | 2015 | F. Gary Gray |
| 812 | The Straight Story | 1999 | David Lynch |
| 1301 | Strange Days | 1995 | Kathryn Bigelow |
| 1404 | Stranger by the Lake | 2013 | Alain Guiraudie |
| 809 | Stranger than Paradise | 1984 | Jim Jarmusch |
| 286 | Strangers on a Train | 1951 | Alfred Hitchcock |
| 2170 | The Strangers | 2008 | Bryan Bertino |
| 1239 | Straw Dogs | 1971 | Sam Peckinpah |
| 2684 | Stray Dog | 1949 | Akira Kurosawa |
| 237 | A Streetcar Named Desire | 1951 | Elia Kazan |
| 1795 | Strike | 1925 | Sergei Eisenstein |
| 2614 | Stripes | 1981 | Ivan Reitman |
| 2563 | Stromboli | 1950 | Roberto Rossellini |
| 2393 | Stroszek | 1977 | Werner Herzog |
| 2829 | The Stunt Man | 1980 | Richard Rush |
| 3028 | Submarine | 2010 | Richard Ayoade |
| 2792 | Suddenly, Last Summer | 1959 | Joseph L. Mankiewicz |
| 2219 | Sugar | 2008 | Anna Boden and Ryan Fleck |
| 2093 | The Suicide Squad | 2021 | James Gunn |
| 389 | Sullivan's Travels | 1941 | Preston Sturges |
| 1988 | Summer | 1986 | Éric Rohmer |
| 1820 | Summer of Soul (...Or, When the Revolution Could Not Be Televised) | 2021 | Questlove |
| 2991 | A Summer's Tale | 1996 | Éric Rohmer |
| 2878 | Summertime | 1955 | David Lean |
| 2736 | Sunday Bloody Sunday | 1971 | John Schlesinger |
| 117 | Sunrise | 1927 | F.W. Murnau |
| 41 | Sunset Blvd. | 1950 | Billy Wilder |
| 1360 | Sunshine | 2007 | Danny Boyle |
| 2451 | Super 8 | 2011 | J.J. Abrams |
| 1714 | Super Fly | 1972 | Gordon Parks Jr. |
| 2157 | Super Size Me | 2004 | Morgan Spurlock |
| 610 | Superbad | 2007 | Greg Mottola |
| 1790 | Supercop | 1992 | Stanley Tong |
| 238 | Superman | 1978 | Richard Donner |
| 723 | Superman II | 1980 | Richard Lester |
| 2980 | El Sur | 1983 | Víctor Erice |
| 2851 | Suspense | 1913 | Phillips Smalley and Lois Weber |
| 2566 | Suspicion | 1941 | Alfred Hitchcock |
| 228 | Suspiria | 1977 | Dario Argento |
| 998 | Sweeney Todd: The Demon Barber of Fleet Street | 2007 | Tim Burton |
| 1427 | The Sweet Hereafter | 1997 | Atom Egoyan |
| 209 | Sweet Smell of Success | 1957 | Alexander Mackendrick |
| 956 | Sweet Sweetback's Baadasssss Song | 1971 | Melvin Van Peebles |
| 2318 | The Swimmer | 1968 | Frank Perry |
| 966 | Swing Time | 1936 | George Stevens |
| 1614 | Swingers | 1996 | Doug Liman |
| 2634 | The Sword in the Stone | 1963 | Wolfgang Reitherman |
| 2724 | Symbiopsychotaxiplasm: Take One | 1968 | William Greaves |
| 2301 | Sympathy for Mr. Vengeance | 2002 | Park Chan-wook |
| 2839 | Syndromes and a Century | 2006 | Apichatpong Weerasethakul |
| 1078 | Synecdoche, New York | 2008 | Charlie Kaufman |
